A Perspective on therapeutic potential of weeds
Main Article Content
Abstract
Nature gives us a diverse plethora of floral wealth. Weeds have been recognized as invasive plant by most of scholars in today’s world with extraordinary travel history. They are considered to be noxious for adjoining plant species and also as economic hazard. Weeds inhabited in almost entire biomes and have capability to survive in harsh conditions of environment thereby become source of inspiration for finding novel phytoconstituents. Weeds play a significant role in absorbing harmful micro pollutants that are affecting ecosystem adversely. There are so many examples like canna lily, bladder wort, coltsfoot, giant buttercup etc. playing crucial part in sustaining environment. Different isolation and characterization approaches like high pressure liquid chromatography, gas chromatography, ion exchange chromatography, nuclear magnetic resonance, mass spectroscopy etc. have also been fetched for obtaining novel constituents from weeds. The main aim of this review is to analyze the therapeutic potential of weeds established in New Zealand and effort to unfold the wide scope of its applications in biological sciences. Upon exploration of various authorized databases available it has been found that weeds not only are the reservoir of complex phytoconstituents exhibiting diverse array of pharmacological activities but also provide potential role in environment phytoremediation. Phytoconstituents reported in weeds have immense potential as a drug targets for different pathological conditions. This review focuses on the literature of therapeutic potential of weeds established in New Zealand and tried to unveil the hidden side of these unwanted plants called weeds.
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Jethro Tull. Horse hoeing husbandary, Berkshire. MDCC, 33; 1731.
Crawley MJ. Biodiversity. In: Crawley, M.J., (ed.) Plant Ecology, 2nd Edn. Blackwell Scientific, Oxford; 1997.
Aldrich RJ, Kremer RJ. Principles in weed management. Iowa State University Press; 1997.
Rao VS. Principles of Weed Science, 2nd Edn, Science Publishers, Enfield, New Hampshire, USA; 2000.
Oudhia P. Medicinal weeds in rice fields of Chhattisgarh, India. International Rice Research Notes. 1999; 24:40.
Gibbons DW, Bohan DA, Rothery P, Stuart RC, Haughton AJ, et al. Weed seed resources for birds in fields with contrasting conventional and genetically modified herbicide-tolerant crops. Proceedings of the Royal Society B: Biological Sciences. 2006; 273: 1921-1928. PubMed: PubMed: https://www.ncbi.nlm.nih.gov/pubmed/16822753
Hawes C, Haughton AJ, Bohan DA, Squire GR. Functional approaches for assessing plant and invertebrate abundance patterns in arable systems. Basic and Applied Ecology. 2009; 10: 34-42.
Kromp B. Carabid beetles in sustainable agriculture: a review on pest control efficacy, cultivation impacts and enhancement. Agriculture, Ecosystems & Environment. 1999; 74: 187-228.
Evans CL. The war on weeds in the Prairie west: an environmental history. University of Calgary Press; 2002.
Popay I, Champion P, James T. An Illustrated Guide to Common Weeds of New Zealand. 3rd Edn. New Zealand Plant Protection Society. 2010.
Hsieh YS, Harris PJ. Structures of xyloglucans in primary cell walls of gymnosperms, monilophytes (ferns sensu lato) and lycophytes. Phytochemistry. 2012; 79: 87-101.
Rasanen RM, Hieta JP, Immanen J, Nieminen K, Haavikko R, et al. Chemical profiles of birch and alder bark by ambient mass spectrometry. Anal Bioanal Chem. 2019; 411: 7573-7583.
Collett MG, Taylor SM. Photosensitising toxins in alligator weed (Alternanthera philoxeroides) likely to be anthraquinones. Toxicon. 2019; 167: 172-173. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31226258
Alipieva K, Evstatieva L, Handjieva N, Popova S. Comparative analysis of the composition of flower volatiles from Lamium L. species and Lamiastrum galeobdolon Heist. ex Fabr. Zeitschrift fur Naturforschung C. 2003; 58: 779-782.
Masi M, Di Lecce R, Tuzi A, Linaldeddu BT, Montecchio L, et al. Hyfraxinic Acid, a Phytotoxic Tetrasubstituted Octanoic Acid, Produced by the Ash (Fraxinus excelsior L.) Pathogen Hymenoscyphus fraxineus Together with Viridiol and Some of Its Analogues. J Agric Food Chem. 2019; 67: 13617-13623. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31661270
Metlicar V, Vovk I, Albreht A. Japanese and Bohemian Knotweeds as Sustainable Sources of Carotenoids. Plants. 2019; 8: 384. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843863/
Alamzeb M, Omer M, Ur-Rashid M, Raza M, Ali S, et al. NMR, Novel Pharmacological and In Silico Docking Studies of Oxyacanthine and Tetrandrine: Bisbenzylisoquinoline Alkaloids Isolated from Berberis glaucocarpa Roots. J Anal Methods Chem. 2018; 7692913. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29888027
Kitryte V, Narkeviciute A, Tamkute L, Syrpas M, Pukalskiene M, et al. Consecutive high-pressure and enzyme assisted fractionation of blackberry (Rubus fruticosus L.) pomace into functional ingredients: Process optimization and product characterization. Food Chem. 2020; 312: 126072. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31893552
Weretilnyk EA, Bednarek S, McCue KF, Rhodes D, Hanson AD. Comparative biochemical and immunological studies of the glycine betaine synthesis pathway in diverse families of dicotyledons. Planta. 1989; 178: 342-352.
Mithofer A, Reichelt M, Nakamura Y. Wound and insect‐induced jasmonate accumulation in carnivorous Drosera capensis: two sides of the same coin. Plant Biol. 2014; 16: 982-987. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/24499476
Małajowicz J, Kusmirek S. Structure and properties of ricin–the toxic protein of Ricinus communis. Postepy Biochemii. 2019; 65: 03-108. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31642648
Cruz-Salas CN, Prieto C, Calderon-Santoyo M, Lagarón JM, Ragazzo-Sanchez JA. Micro-and Nanostructures of Agave Fructans to Stabilize Compounds of High Biological Value via Electrohydrodynamic Processing. Nanomaterials. 2019; 9:1659. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31766573
Sendker J, Ellendorff T, Holzenbein A. Occurrence of benzoic acid esters as putative catabolites of prunasin in senescent leaves of Prunus laurocerasus. J Nat Prod. 2016; 79: 1724-1729. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/27331617
Bridi R, Giordano A, Penailillo MF, Montenegro G. Antioxidant Effect of Extracts from Native Chilean Plants on the Lipoperoxidation and Protein Oxidation of Bovine Muscle. Molecules. 2019; 24: 3264. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31500282
Ouyang MA, He ZD, Wu CL. Anti-oxidative activity of glycosides from Ligustrum sinense. Natural product research. 2003; 17: 381-387. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/14577686
Ben Ammar R, Miyamoto T, Chekir-Ghedira L, Ghedira K, Lacaille-Dubois MA. Isolation and identification of new anthraquinones from Rhamnus alaternus L and evaluation of their free radical scavenging activity. Natural product research. 2019; 33: 280-286. PubMed: https://pubmed.ncbi.nlm.nih.gov/29533086/
Matouskova M, Jurova J, Grulova D, Wajs-Bonikowska A, Renco M, Sedlak V, Poracova J, Gogalova Z, Kalemba D. Phytotoxic Effect of Invasive Heracleum mantegazzianum Essential Oil on Dicot and Monocot Species. Molecules. 2019; 24: 425. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384721/
Lachowicz S, Oszmianski J. Profile of Bioactive Compounds in the Morphological Parts of Wild Fallopia japonica (Houtt) and Fallopia sachalinensis (F. Schmidt) and Their Antioxidative Activity. Molecules. 2019; 24: 1436. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30979044
Liu QR, Li J, Zhao XF, Xu B, Xiao XH, et al. Alkaloids and phenylpropanoid from Rhizomes of Arundo donax L. Natural Product Res. 2019: 1-6.
Ikbal C, Habib B, Hichem BJ, Monia BH, Habib BH, et al. Purification of a natural insecticidal substance from Cestrum parqui (Solanaceae). Pak J Biol Sci. 2007; 10: 3822-3828. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/19090236
Mandim F, Barros L, Heleno SA, Pires TC, Dias MI, Alves MJ, Santos PF, Ferreira IC. Phenolic profile and effects of acetone fractions obtained from the inflorescences of Calluna vulgaris (L.) Hull on vaginal pathogenic and non-pathogenic bacteria. Food & Function. 2019; 10: 2399-2407. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31049501
Zhang T, Liu H, Bai X, Liu P, Yang Y, et al. Fractionation and antioxidant activities of the water-soluble polysaccharides from Lonicera japonica Thunb. International journal of biological macromolecules. 2019. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31739015
Matthaus B, Ozcan MM. Fatty acid, tocopherol and squalene contents of Rosaceae seed oils. Botanical studies. 2014; 55:48. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432826/
Jo MS, Yu JS, Lee JC, Lee S, Cho YC, et al. Lobatamunsolides A–C, Norlignans from the Roots of Pueraria lobata and their Nitric Oxide Inhibitory Activities in Macrophages. Biomolecules. 2019; 9:755. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31757072
Fu Y, Li F, Ding Y, Li HY, Xiang XR, et al. Polysaccharides from loquat (Eriobotrya japonica) leaves: Impacts of extraction methods on their physicochemical characteristics and biological activities. Int J Biol Macromolecules. 2020. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31923490
Chu MJ, Du YM, Liu XM, Yan N, Wang FZ, et al. Extraction of proanthocyanidins from chinese wild rice (zizania latifolia) and analyses of structural composition and potential bioactivities of different fractions. Molecules. 2019; 24:1681. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31052148
Dong LM, Zhang M, Xu QL, Zhang Q, Luo B, et al. Two new thymol derivatives from the roots of Ageratina adenophora. Molecules. 2017; 22: 592. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154539/
Zhang ZP, Shen CC, Gao FL, Wei H, Ren DF, et al. Isolation, purification and structural characterization of two novel water-soluble polysaccharides from Anredera cordifolia. Molecules. 2017; 22: 1276. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28769023
Priolo N, Del Valle SM, Arribere MC, López L, Caffini N. Isolation and characterization of a cysteine protease from the latex of Araujia hortorum fruits. Journal of Protein Chemistry. 2000; 19: 39-49.
Akihara Y, Kamikawa S, Harauchi Y, Ohta E, Nehira T, et al. HPLC profiles and spectroscopic data of cassane-type furanoditerpenoids. Data in brief. 2018; 21:1076-88. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30450403
Jordheim M, Calcott K, Gould KS, Davies KM, Schwinn KE, et al. High concentrations of aromatic acylated anthocyanins found in cauline hairs in Plectranthus ciliatus. Phytochemistry. 2016; 128:27-34. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/27165277
Boppre M, Colegate SM. Recognition of pyrrolizidine alkaloid esters in the invasive aquatic plant Gymnocoronis spilanthoides (Asteraceae). Phytochemical Analysis. 2015; 26: 215-225.
Du YQ, Yan ZY, Chen JJ, Wang XB, Huang XX, et al. The identification of phenylpropanoids isolated from the root bark of Ailanthus altissima (Mill.) Swingle. Nat Product Res. 2019: 1-8. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31315448
El-Tantawy ME, Shams MM, Afifi MS. Chemical composition and biological evaluation of the volatile constituents from the aerial parts of Nephrolepis exaltata (L.) and Nephrolepis cordifolia (L.) C. Presl grown in Egypt. Natural product research. 2016; 30: 1197-201. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/26211503
Matsuda H, Nakashima S, Abdel-Halim OB, Morikawa T, Yoshikawa M. Cucurbitane-type triterpenes with anti-proliferative effects on U937 cells from an egyptian natural medicine, Bryonia cretica: structures of new triterpene glycosides, bryoniaosides A and B. Chemical and Pharmaceutical Bulletin. 2010; 58: 747-51. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/20460809
Kisielius V, Lindqvist DN, Thygesen MB, Rodamer M, Hansen HC, Rasmussen LH. Fast LC-MS quantification of ptesculentoside, caudatoside, ptaquiloside and corresponding pterosins in bracken ferns. J Chromatography B. 2020: 121966. PubMed: https://pubmed.ncbi.nlm.nih.gov/31931331
Shulha O, Çiçek SS, Wangensteen H, Kroes J, Mäder M, et al. Lignans and sesquiterpene lactones from Hypochaeris radicata subsp. neapolitana (Asteraceae, Cichorieae). Phytochemistry. 2019; 165: 112047.
Khan WN, Lodhi MA, Ali I, Azhar-Ul-Haq, Malik A, et al. New natural urease inhibitors from Ranunculus repens. J Enzyme Inhibition Med Chem. 2006; 21: 17-19. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/16570500
Neag T, Olah NK, Hanganu D, Benedec D, Pripon FF, et al. The anemonin content of four different Ranunculus species. Pakistan J Pharmaceutical Sci. 2018; 31: 2027-2032. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30393208
Mabona U, Viljoen A, Shikanga E, Marston A, Van Vuuren S. Antimicrobial activity of southern African medicinal plants with dermatological relevance: from an ethnopharmacological screening approach, to combination studies and the isolation of a bioactive compound. J Ethnopharmacol. 2013; 148: 45-55. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/23545456
You Y, Kim K, Yoon HG, Lee KW, Lee J, et al. Chronic effect of ferulic acid from Pseudosasa japonica leaves on enhancing exercise activity in mice. Phytotherapy Res. 2010; 24: 1508-1513. PubMed: https://pubs.acs.org/doi/abs/10.1021/jf010514x
Matos P, Figueirinha A, Ferreira I, Cruz MT, Batista MT. Acanthus mollis L. leaves as source of anti-inflammatory and antioxidant phytoconstituents. Natural product research. 2019; 33: 1824-1827. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29417845
Santos-Rebelo A, Garcia C, Eleuterio C, Bastos A, Castro Coelho S, et al. Development of Parvifloron D-Loaded Smart Nanoparticles to Target Pancreatic Cancer. Pharmaceutics. 2018; 10: 216. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321128/
Feng X, Wang X, Liu Y, Di X. Linarin inhibits the acetylcholinesterase activity in-vitro and ex-vivo. Iranian journal of pharmaceutical research: IJPR. 2015; 14: 949. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518125/
Saini NK, Singha M. Anti–inflammatory, analgesic and antipyretic activity of methanolic Tecomaria capensis leaves extract. Asian Pac J Trop Biomed. 2012; 2: 870-874. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609241/
Aboutabl EA, Hashem FA, Sleem AA, Maamoon AA. Flavonoids, anti-inflammatory activity and cytotoxicity of Macfadyena unguis-cati L. Afr J Tradit Complement Altern Med. 2008; 5: 18-26. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816596/
Park SH, Jang S, Lee SW, Park SD, Sung YY, et al. Akebia quinata Decaisne aqueous extract acts as a novel anti-fatigue agent in mice exposed to chronic restraint stress. J Ethnopharmacol. 2018; 222: 270-279. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29630998
Guesmi F, Hmed MB, Prasad S, Tyagi AK, Landoulsi A. in vivo pathogenesis of colon carcinoma and its suppression by hydrophilic fractions of Clematis flammula via activation of TRAIL death machinery (DRs) expression. Biomedicine & Pharmacotherapy. 2019; 109: 2182-2191.
Chu Z, Wang H, Ni T, Tao L, Xiang L, et al. 28-Hydroxy-3-oxoolean-12-en-29-oic Acid, a Triterpene Acid from Celastrus orbiculatus Extract, Inhibits the Migration and Invasion of Human Gastric Cancer Cells in vitro. Molecules. 2019; 24: 3513. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31569766
Habtemariam S. The therapeutic potential of Berberis darwinii stem-bark: quantification of berberine and in vitro evidence for Alzheimer's disease therapy. Nat Prod Commun. 2011; 6: 1089-1090. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/21922905
Topolska J, Kostecka-Gugała A, Ostachowicz B, Latowski D. Selected metal content and antioxidant capacity of Sambucus nigra flowers from the urban areas versus soil parameters and traffic intensity. Environ Sci Pollut Res Int. 2020; 27: 668-677. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31808083
Packer J, Naz T, Harrington D, Jamie JF, Vemulpad SR. Antimicrobial activity of customary medicinal plants of the Yaegl Aboriginal community of northern New South Wales, Australia: a preliminary study. BMC Res Notes. 2015; 8: 276. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/26122212
Kim HS, Jang JM, Yun SY, Zhou D, Piao Y, et al. Effect of Robinia pseudoacacia Leaf Extract on Interleukin-1β–mediated Tumor Angiogenesis. in vivo. 2019; 33: 1901-1910. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31662518
Nawwar M, Swilam N, Hashim A, Al-Abd A, Abdel-Naim A, et al. Cytotoxic isoferulic acidamide from Myricaria germanica (Tamaricaceae). Plant Signal Behav. 2013; 8: e22642. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745567/
Patova OA, Smirnov VV, Golovchenko VV, Vityazev FV, Shashkov AS, et al. Structural, rheological and antioxidant properties of pectins from Equisetum arvense L. and Equisetum sylvaticum L. Carbohydrate Polymers. 2019; 209: 239-249.
Calderon-Montano JM, Martinez-Sanchez SM, Burgos-Moron E, Guillen-Mancina E, Jimenez-Alonso JJ, et al. Screening for selective anticancer activity of plants from Grazalema Natural Park, Spain. Nat Prod Res. 2019; 33: 3454345-8. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29842791
Pires AS, Rigueiras PO, Dohms SM, Porto WF, Franco OL. Structure‐guided identification of antimicrobial peptides in the spathe transcriptome of the non‐model plant, arum lily (Zantedeschia aethiopica). Chem Biol Drug Design. 2019; 93: 1265-1275.
Radulovic N, Denic M, Stojanovic-Radic Z. Antimicrobial phenolic abietane diterpene from Lycopus europaeus L.(Lamiaceae). Bioorg Med Chem Lett. 2010; 20: 4988-4891. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/20674349
Chen X, Li T, Qing D, Chen J, Zhang Q, et al. Structural characterization and osteogenic bioactivities of a novel Humulus lupulus polysaccharide. Food Function. 2020; 11: 1165-1175. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31872841
Bournine L, Bensalem S, Wauters JN, Iguer-Ouada M, Maiza-Benabdesselam F, et al.. Identification and quantification of the main active anticancer alkaloids from the root of Glaucium flavum. Int J Mol Sci. 2013; 14: 23533-23544. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876061/
Basic M, Elgner F, Bender D, Sabino C, Herrlein ML, et al. A synthetic derivative of houttuynoid B prevents cell entry of Zika virus. Antiviral Res. 2019; 172: 104644. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31697958
Akhtar M, Shaukat A, Zahoor A, Chen Y, Wang Y, et al.. Anti-inflammatory effects of Hederacoside-C on Staphylococcus aureus induced inflammation via TLRs and their downstream signal pathway in vivo and in vitro. Microbial Pathogenesis. 2019; 137: 103767. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31580956
García ME, Borioni JL, Cavallaro V, Puiatti M, Pierini AB, et al. Solanocapsine derivatives as potential inhibitors of acetylcholinesterase: Synthesis, molecular docking and biological studies. Steroids. 2015; 104: 95-110. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/26362598
Dougnon G, Ito M. Sedative effects of the essential oil from the leaves of Lantana camara occurring in the Republic of Benin via inhalation in mice. J Nat Med. 2020; 74: 159-169. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31446559
Hsu CL, Fang SC, Yen GC. Anti-inflammatory effects of phenolic compounds isolated from the flowers of Persicaria hydropiperPersicaria hydropiper Zucc. Food & function. 2013; 4: 1216-1222. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/23727892
Ticona LA, SAnchez AR, GonzAles OO, Domenech MO. Antimicrobial compounds isolated from Tropaeolum tuberosum. Natural Product Research. 2020: 1-5. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31913056
Luis A, Breitenfeld L, Ferreira S, Duarte AP, Domingues F. Antimicrobial, antibiofilm and cytotoxic activities of Hakea sericea Schrader extracts. Pharmacognosy magazine. 2014; 10: S6. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/24914310
Yesilada E, Kupeli E. Clematis vitalba L. aerial part exhibits potent anti-inflammatory, antinociceptive and antipyretic effects. J Ethnopharmacol. 2007; 110: 504-515.
Amabeoku GJ, Green I, Kabatende J. Anticonvulsant activity of Cotyledon orbiculata L.(Crassulaceae) leaf extract in mice. J Ethnopharmacol. 2007; 112: 101-107. PubMed: https://pubmed.ncbi.nlm.nih.gov/17398051
Neuman MG, Jia AY, Steenkamp V. Senecio latifolius induces in vitro hepatocytotoxicity in a human cell line. Canadian journal of physiology and pharmacology. 2007; 85: 1063-1075.
dos Santos Alves CF, Bonez PC, de Souza MD, da Cruz RC, Boligon AA, et al. Antimicrobial, antitrypanosomal and antibiofilm activity of Equisetum hyemale. Microbial pathogenesis. 2016; 101: 119-125. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/27856271
Schmidt M, Skaf J, Gavril G, Polednik C, Roller J, et al. The influence of Osmunda regalis root extract on head and neck cancer cell proliferation, invasion and gene expression. BMC Complement Altern Med. 2017; 17: 518. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716017/
Tian G, Chen J, Luo Y, Yang J, Gao T, Shi J. Ethanol extract of Ligustrum lucidum Ait. leaves suppressed hepatocellular carcinoma in vitro and in vivo. Cancer Cell Int. 2019; 19: 246. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31572063
Saddiqe Z, Maimoona A, Abbas G, Naeem I, Shahzad M. Pharmacological screening of Hypericum androsaemum extracts for antioxidant, anti-lipid peroxidation, antiglycation and cytotoxicity activity. Pakistan J Pharmaceut Sci. 2016; 29.
Tiana C, Yang C, Zhang D, Han L, Liu Y, et al. Antibacterial and antioxidant properties of various solvents extracts of Abutilon theophrasti Medic. leaves. Pak J Pharmaceut Sci. 2017; 30. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28653920
Ling B, Xiao S, Yang J, Wei Y, Sakharkar MK, et al. Probing the Antitumor Mechanism of Solanum nigrum L. Aqueous Extract against Human Breast Cancer MCF7 Cells. Bioengineering. 2019; 6: 112. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31835887
Aghajanyan A, Nikoyan A, Trchounian A. Biochemical activity and hypoglycemic effects of Rumex obtusifolius L. seeds used in Armenian traditional medicine. BioMed research international. 2018; 2018.
Boniface PK, Verma S, Shukla A, Cheema HS, Srivastava SK, et al. Bioactivity-guided isolation of antiplasmodial constituents from Conyza sumatrensis (Retz.) EH Walker. Parasitol Int. 2015; 64: 118-123. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/25449289
Genc Y, Dereli FT, Saracoglu I, Akkol EK. The inhibitory effects of isolated constituents from Plantago major subsp. major L. on collagenase, elastase and hyaluronidase enzymes: Potential wound healer. Saudi Pharmaceut J. 2020; 28: 101-106. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31920436
Rogozhin EA, Slezina MP, Slavokhotova AA, Istomina EA, Korostyleva TV, et al. A novel antifungal peptide from leaves of the weed Stellaria media L. Biochimie. 2015; 116: 125-132. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/26196691
Ilina T, Kashpur N, Granica S, Bazylko A, Shinkovenko I, et al. Phytochemical Profiles and in vitro Immunomodulatory Activity of Ethanolic Extracts from Galium aparine L. Plants. 2019; 8: 541. PubMed: https://pubmed.ncbi.nlm.nih.gov/31775336
Aremu OO, Oyedeji AO, Oyedeji OO, Nkeh-Chungag BN, Rusike CR. in vitro and in vivo Antioxidant Properties of Taraxacum officinale in Nω-Nitro-l-Arginine Methyl Ester (L-NAME)-Induced Hypertensive Rats. Antioxidants. 2019; 8: 309. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31443195
Jahan S, Azad T, Ayub A, Ullah A, Afsar T, et al. Ameliorating potency of Chenopodium album Linn. and vitamin C against mercuric chloride-induced oxidative stress in testes of Sprague Dawley rats. Environ Health Prevent Med. 2019; 24: 62.
Parzonko A, Kiss AK. Caffeic acid derivatives isolated from Galinsoga parviflora herb protected human dermal fibroblasts from UVA-radiation. Phytomedicine. 2019; 57: 215-22. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30785017
Di Sotto A, Di Giacomo S, Toniolo C, Nicoletti M, Mazzanti G. Sisymbrium Officinale (L.) Scop. and its polyphenolic fractions inhibit the mutagenicity of Tert‐butylhydroperoxide in Escherichia Coli WP2uvrAR strain. Phytotherapy Res. 2016; 30: 829-834.
Di Napoli M, Varcamonti M, Basile A, Bruno M, Maggi F, et al. Anti-Pseudomonas aeruginosa activity of hemlock (Conium maculatum, Apiaceae) essential oil. Nat Prod Res. 2019; 33: 3436-3440.
Song SY, Hyun JE, Kang JH, Hwang CY. in vitro antibacterial activity of the manuka essential oil from Leptospermum scoparium combined with Tris‐EDTA against Gram‐negative bacterial isolates from dogs with otitis externa. Vet Dermatol. 2019.
Doukkali Z, Taghzouti K, Bouidida EH, Nadjmouddine M, Cherrah Y, et al. Evaluation of anxiolytic activity of methanolic extract of Urtica urens in a mice model. Behav Brain Funct. 2015; 11: 19. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423131/
Farid O, Zeggwagh NA, Ouadi FE, Eddouks M. Mentha pulegium Aqueous Extract Exhibits Antidiabetic and Hepatoprotective Effects in Streptozotocin-induced Diabetic Rats. Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets-Immune, Endocrine & Metabolic Disorders). 2019; 19: 292-301. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30289084
Bubueanu C, Iuksel R, Panteli M. Haemostatic activity of butanolic extracts of Lamium album and Lamium purpureum aerial parts. Acta Pharmaceutica. 2019; 69: 443-449. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31259737
Ibrahim AM, Ghoname SI. Molluscicidal impacts of Anagallis arvensis aqueous extract on biological, hormonal, histological and molecular aspects of Biomphalaria alexandrina snails. Experimental Parasitology. 2018; 192: 36-41.
Fernandez-Martinez E, Jimenez-Santana M, Centeno-Alvarez M, Torres-Valencia JM, Shibayama M, et al. Hepatoprotective effects of nonpolar extracts from inflorescences of thistles Cirsium vulgare and Cirsium ehrenbergii on acute liver damage in rat. Pharmacognosy magazine. 2017; 13: S860. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822512/
Sharifi-Rad J, Iriti M, Setzer WN, Sharifi-Rad M, Roointan A, et al. Antiviral activity of Veronica persica Poir. on herpes virus infection. Cell Mol Biol. 2018; 64: 11-17. PubMed: https://pubmed.ncbi.nlm.nih.gov/29981678
Li BY, Hu Y, Li J, Shi K, Shen YF, et al. Ursolic acid from Prunella vulgaris L. efficiently inhibits IHNV infection in vitro and in vivo. Virus Res. 2019; 273: 197741.
Torres-GonzAlez L, Cienfuegos-Pecina E, Perales-Quintana MM, Alarcon-Galvan G, Munoz-Espinosa LE, et al. Nephroprotective effect of Sonchus oleraceus extract against kidney injury induced by ischemia-reperfusion in wistar rats. Oxidative medicine and cellular longevity. 2018; 2018: 9572803. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29643981
Ayaz M, Ahmad I, Sadiq A, Ullah F, Ovais M, Khalil AT, Devkota HP. Persicaria hydropiper (L.) Delarbre: A review on traditional uses, bioactive chemical constituents and pharmacological and toxicological activities. Journal of Ethnopharmacology. 2019: 112516. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31884037
Guz L, Adaszek L, Wawrzykowski J, Zietek J, Winiarczyk S. in vitro antioxidant and antibabesial activities of the extracts of Achillea millefolium. Polish journal of veterinary sciences. 2019: 369-376. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31269341
Mahdavi S, Amiradalat M, Babashpour M, Sheikhlooei H, Miransari M. The antioxidant, anticarcinogenic and antimicrobial properties of Verbascum thapsus L. Medicinal chemistry (Shariqah (United Arab Emirates)). 2019. PubMed: https://pubmed.ncbi.nlm.nih.gov/31456524
Oszmianski J, Wojdyło A, Juszczyk P, Nowicka P. Roots and Leaf Extracts of Dipsacus fullonum L. and Their Biological Activities. Plants. 2020; 9: 78. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31936189
Kim J, Jung KH, Ryu HW, Kim DY, Oh SR, et al. Apoptotic Effects of Xanthium strumarium via PI3K/AKT/mTOR Pathway in Hepatocellular Carcinoma. Evidence-Based Complementary and Alternative Medicine. 2019; 2019.
Shiomi N, editor. Advances in Bioremediation and Phytoremediation. BoD–Books on Demand; 2018.
Macci C, Peruzzi E, Doni S, Iannelli R, Masciandaro G. Ornamental plants for micropollutant removal in wetland systems. Environ Sci Pollut Res. 2015; 22: 2406-2415. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/24798922
Augustynowicz J, Lukowicz K, Tokarz K, Płachno BJ. Potential for chromium (VI) bioremediation by the aquatic carnivorous plant Utricularia gibba L. (Lentibulariaceae). Environ Sci Pollut Res. 2015; 22: 9742-9748.
Cui X, Fang S, Yao Y, Li T, Ni Q, et al. Potential mechanisms of cadmium removal from aqueous solution by Canna indica derived biochar. Sci Total Environ. 2016; 562: 517-525. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/27107650
Wechtler L, Laval-Gilly P, Bianconi O, Walderdorff L, Bonnefoy A, et al. Trace metal uptake by native plants growing on a brownfield in France: zinc accumulation by Tussilago farfara L. Environ Sci Pollut Res . 2019; 26: 36055-36062
Maleva M, Garmash E, Chukina N, Malec P, Waloszek A, et al. Effect of the exogenous anthocyanin extract on key metabolic pathways and antioxidant status of Brazilian elodea (Egeria densa (Planch.) Casp.) exposed to cadmium and manganese. Ecotoxicol Environ Safety. 2018; 160: 197-206.
Marchand L, Lamy P, Bert V, Quintela-Sabaris C, Mench M. Potential of Ranunculus acris L. for biomonitoring trace element contamination of riverbank soils: photosystem II activity and phenotypic responses for two soil series. Environ Sci Pollut Res . 2016; 23: 3104-3119. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/25956517
Pardo-Muras M, G Puig C, Pedrol N. Cytisus scoparius and Ulex europaeus Produce Volatile Organic Compounds with Powerful Synergistic Herbicidal Effects. Molecules. 2019; 24: 4539. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943486/
Salinitro M, Tassoni A, Casolari S, de Laurentiis F, Zappi A, et al. Heavy Metals Bioindication Potential of the Common Weeds Senecio vulgaris L., Polygonum aviculare L. and Poa annua L. Molecules. 2019; 24: 2813. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31374997
Guo X, Wang P, Li Y, Zhong H, Li P, et al. Effect of copper on the removal of tetracycline from water by Myriophyllum aquaticum: Performance and mechanisms. Bioresource Technol. 2019; 291: 121916. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31377514
Noori A, Zare Maivan H, Alaie E, Newman LA. Leucanthemum vulgare Lam. crude oil phytoremediation. Int J Phytoremediation. 2018; 20: 1292-1299. PubMed: https://pubmed.ncbi.nlm.nih.gov/26121329
Yu X, Brown JM, Graham SE, Carbajal EM, Zuleta MC, Milla-Lewis SR. Detection of quantitative trait loci associated with drought tolerance in St. Augustinegrass. PloS one. 2019; 14. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31671135
Alur HH, Pather SI, Mitra AK, Johnston TP. Evaluation of the gum from Hakea gibbosa as a sustained-release and mucoadhesive component in buccal tablets. Pharmaceutical development and technology. 1999; 4: 347-358. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/10434280
Keshari AK, Srivastava R, Singh P, Yadav VB, Nath G. Antioxidant and antibacterial activity of silver nanoparticles synthesized by Cestrum nocturnum. J Ayurveda Integrative Med. 2018.
Hussain N, Abbasi T, Abbasi SA. Generation of highly potent organic fertilizer from pernicious aquatic weed Salvinia molesta. Environ Sci Pollut Res Int. 2018; 25: 4989-5002. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29209963
Balsamo RA, Willigen CV, Bauer AM, Farrant J. Drought tolerance of selected Eragrostis species correlates with leaf tensile properties. Ann Botany. 2006; 97: 985-991.
Zhou Y, Lambrides CJ, Kearns R, Ye C, Fukai S. Water use, water use efficiency and drought resistance among warm-season turfgrasses in shallow soil profiles. Functional plant biology. 2012; 39: 116-125. PubMed: https://www.publish.csiro.au/fp/FP11244
Baracho NC, Vicente BB, Arruda GD, Sanches BC, Brito JD. Study of acute hepatotoxicity of Equisetum arvense L. in rats. Acta Cirurgica Brasileira. 2009; 24: 449-453. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/20011829/
Slaughter RJ, Beasley DM, Lambie BS, Wilkins GT, Schep LJ. Poisonous plants in New Zealand: a review of those that are most commonly enquired about to the National Poisons Centre. N Z Med J. 2012; 125: 87-118. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/23321887
Bregnbak D, Menné T, Johansen JD. Airborne contact dermatitis caused by common ivy (Hedera helix L. ssp. helix). Contact Dermatitis. 2015; 72: 243-244. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/25630853
Pour BM, Sasidharan S. in vivo toxicity study of Lantana camara. Asian Pac J Trop Biomed. 2011; 1: 230-232. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609184/
Botha CJ, Lessing D, Rösemann M, Van Wilpe E, Williams JH. Analytical confirmation of Xanthium strumarium poisoning in cattle. J Vet Diagn Invest. 2014; 26: 640-645. PubMed: https://pubmed.ncbi.nlm.nih.gov/25012081